World IBD Day

19 May 2024

World IBD Day takes place on 19 May each year and unites people worldwide in their fight against Crohn's disease and ulcerative colitis, known as inflammatory bowel diseases. On World IBD Day we want to raise awareness about this disease, urge governments and healthcare professionals to take action and to show support to the ten million people worldwide that live with IBD. World IBD Day

UpToDate

Adults

• Approach to functional gastrointestinal symptoms in adults with inflammatory bowel disease
• Clinical manifestations, diagnosis, and prognosis of ulcerative colitis in adults
• Clinical manifestations, diagnosis, and prognosis of Crohn disease in adults

Diagnosis

• Clinical manifestations and diagnosis of arthritis associated with inflammatory bowel disease and other gastrointestinal diseases
• Endoscopic diagnosis of inflammatory bowel disease in adults

General

• Clinical manifestations and complications of inflammatory bowel disease in children and adolescents
• Overview of hepatobiliary disorders in patients with inflammatory bowel disease
• Thiopurines: Pretreatment testing and approach to therapeutic drug monitoring for adults with inflammatory bowel disease
• Dermatologic and ocular manifestations of inflammatory bowel disease
• Fertility, pregnancy, and nursing in inflammatory bowel disease
• Vitamin and mineral deficiencies in inflammatory bowel disease
• Pulmonary complications of inflammatory bowel disease
• Metabolic bone disease in inflammatory bowel disease

Paediatrics

• Clinical presentation and diagnosis of inflammatory bowel disease in children
• Growth failure and pubertal delay in children with inflammatory bowel disease
• Important health maintenance issues for children and adolescents with inflammatory bowel disease

Risks

• Definitions, epidemiology, and risk factors for inflammatory bowel disease

Treatment

• Overview of azathioprine and mercaptopurine use in inflammatory bowel disease
• Overview of the management of Crohn disease in children and adolescents
• Medical therapies for Crohn disease in children and adolescents
• Management of mild to moderate ulcerative colitis in children and adolescents
• Overview of the medical management of mild (low risk) Crohn disease in adults
• Overview of budesonide therapy for adults with inflammatory bowel disease
• Surgical management of ulcerative colitis
• Nutrition and dietary management for adults with inflammatory bowel disease
• Medical management of low-risk adult patients with mild to moderate ulcerative colitis
• Management of Crohn disease after surgical resection

Cochrane Library

• Prebiotics for induction and maintenance of remission in ulcerative colitis
• Vitamin D for the treatment of inflammatory bowel disease
• Vedolizumab for induction and maintenance of remission in Crohn's disease
• Remote care through telehealth for people with inflammatory bowel disease
• Patient education interventions for the management of inflammatory bowel disease
• Fecal transplantation for treatment of inflammatory bowel disease
• Preoperative combined mechanical and oral antibiotic bowel preparation for preventing complications in elective colorectal surgery

Clinical resources

• Management overview of IBD (Gastrointestinal Society of Australia)
• Inflammatory bowel disease national action plan (Australian Government)
• Clinical update for General Practitioners and Physicians Inflammatory bowel disease updated 2018 (Gastrointestinal Society of Australia)
• ESPEN guideline on Clinical Nutrition in inflammatory bowel disease (European Society for Clinical Nutrition and Metabolism)

Online resources

• Crohn’s & Colitis Australia
• IBD Resource Kit (Ferring Pharmaceuticals Australia)
• Tame your gut
• MindOverGut
• IBD passport

Articles

Diagnosis

• The role of faecal calprotectin in the diagnosis of inflammatory bowel disease
• Exploring the gut microbiome’s role in Inflammatory Bowel Disease: Insights and interventions
• Establishing a machine learning model based on dual-energy CT enterography to evaluate Crohn’s disease activity
• Biomarkers in inflammatory bowel disease: a practical guide

Research

• Pediatric to adult transition in inflammatory bowel disease: Consensus Guidelines for Australia and New Zealand
• Transitional care of adolescents with inflammatory bowel disease to adult services varies widely across Australia and New Zealand
• High prevalence of Crohn disease and ulcerative colitis among older people in Sydney
• Patterns of vitamin D testing and supplementation for children with inflammatory bowel disease in Australasia
• Association of ultra-processed food intake with risk of inflammatory bowel disease: prospective cohort study
• Proportion of inflammatory bowel diseases patients with suboptimal disease control in daily clinical practice—Real-world evidence from the inflammatory bowel diseases-podcast study
• Physical activity in the prevention and management of inflammatory bowel disease: a systematic review
• Is the European Crohn’s and Colitis organisation (ECCO) e-guide an acceptable and feasible tool for increasing gastroenterologists’ guideline adherence? A mixed methods evaluation
• The epidemiology of Inflammatory Bowel Disease in Oceania: A systematic review and meta-analysis of incidence and prevalence
• Adherence to endoscopic surveillance guidelines for patients with inflammatory bowel disease: An Australian cohort study

Treatment

• Update for surgeons on novel induction treatments for acute severe inflammatory bowel disease associated colitis
• Trends in targeted therapy usage in Inflammatory Bowel Disease: TRENDY study of ENEIDA
• The effect of probiotics on inflammatory bowel disease remission and relapse rate: A systematic review and meta-analysis
• Therapeutic sequencing in inflammatory bowel disease: Determining the optimal position of vedolizumab for long-term Crohn’s disease control using real-world evidence
• Difficult-to-treat inflammatory bowel disease: Effectiveness and safety of 4th and 5th lines of treatment
• People with Inflammatory Bowel Disease prefer Cognitive Behavioral Therapy for fatigue management: A conjoint analysis
• Steroid therapy in patients with inflammatory bowel disease complicating diabetes diagnosis

E-books

• A sample of e-books available via the library catalogue

E-journals

• A sample of e-journals available via the library catalogue

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Articles

Diagnosis

The role of faecal calprotectin in the diagnosis of inflammatory bowel disease
What you need to know

• Faecal calprotectin testing is recommended in patients <60 years old with lower gastrointestinal symptoms and normal initial workup to exclude causes of colonic inflammation
• A normal faecal calprotectin result has a high negative predictive value for inflammatory bowel disease, and prevents unnecessary investigation when the most likely diagnosis is irritable bowel syndrome
• Faecal calprotectin should not be used in patients older than 60 or if colorectal cancer is suspected
• Faecal calprotectin is a sensitive marker of intestinal inflammation and may be elevated in conditions other than inflammatory bowel disease, such as diverticulitis and infectious gastroenteritis, or when patients take medications such as non-steroidal anti-inflammatory drugs (NSAIDs) and aspirin

BMJ 13 February 2023

Exploring the gut microbiome’s role in Inflammatory Bowel Disease: Insights and interventions
This review explores diagnostic approaches to IBD that integrate clinical assessment with advanced microbiological analyses, highlighting the potential of microbiome profiling as a non-invasive diagnostic tool. In addition, it evaluates conventional and emerging treatments and discusses microbiome-targeted intervention prospects, such as probiotics, symbiotics, and faecal microbiota transplantation. The necessity for future research to establish their efficacy and safety is emphasised. Journal of personalized medicine 11 May 2024

Establishing a machine learning model based on dual-energy CT enterography to evaluate Crohn’s disease activity
Key Points

• Dual-energy CT parameters are related to Crohn’s disease activity.
• Three machine learning models effectively evaluated Crohn’s disease activity.
• Combined models based on conventional and dual-energy CT have the best performance.

Insights into imaging 12 May 2024

Biomarkers in inflammatory bowel disease: a practical guide
Inflammatory bowel disease (IBD) is a term used to describe two conditions, ulcerative colitis (UC) and Crohn’s disease (CD). These two diseases cause inflammation of the bowel, which can lead to diarrhoea, abdominal pain and bleeding from the back passage. The best way of assessing how active a patient’s IBD is, is by performing a camera test called a colonoscopy. However, having a colonoscopy is inconvenient, comes with some risks to the patient, and uses a lot of healthcare resources. ‘Biomarkers’ are proteins detectable in body fluids (such as blood, poo and urine) which can give information to medical staff about how active a patient’s disease is, without the need for colonoscopy. In this article, the authors give guidance about how best to use these tests, and when they might not be so useful. They also discuss new biomarkers and ways in which they could be used in the future to predict which treatments patients might respond to best. Therapeutic advances in gastroenterology 9 May 2024

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Research

Pediatric to adult transition in inflammatory bowel disease: Consensus Guidelines for Australia and New Zealand
A multidisciplinary group devised consensus statements to optimize pediatric to adult transitional care for adolescents with IBD. These guidelines should support improved and standardized delivery of IBD transitional care within Australasia. Inflammatory bowel diseases 3 May 2023

Transitional care of adolescents with inflammatory bowel disease to adult services varies widely across Australia and New Zealand
This survey highlighted that transition care for adolescents with IBD is variable across Australasia. Australasian guideline development may optimize the transition process for adolescents with IBD and improve their longitudinal outcomes. JGH open 17 January 2024

High prevalence of Crohn disease and ulcerative colitis among older people in Sydney
The known: The prevalence of inflammatory bowel disease (IBD) is increasing worldwide. However, recent age‐standardised prevalence data for Australia are not available.
The new: The age‐standardised IBD prevalence rate of 348 cases per 100 000 population we found is the highest ever reported in Australia. Its prevalence was higher in older people: 612 per 100 000 people aged 65 years or more and 891 per 100 000 people aged 85 years or more.
The implications: Given the higher prevalence of IBD among older people in metropolitan Sydney, and their higher risk of infections, doctors should consider replacing systemic immunosuppressive therapies with alternatives when possible. MJA 8 February 2021

Patterns of vitamin D testing and supplementation for children with inflammatory bowel disease in Australasia
The results indicate that standardized guidelines for vitamin D testing and supplementation for clinicians caring for children with IBD throughout Australasia are required. Consensus statements may optimize the care of children with IBD in this diverse geographical region. JGH open 4 March 2024

Association of ultra-processed food intake with risk of inflammatory bowel disease: prospective cohort study
Higher intake of ultra-processed food was positively associated with risk of IBD. Further studies are needed to identify the contributory factors within ultra-processed foods. BMJ 15 July 2021

Proportion of inflammatory bowel diseases patients with suboptimal disease control in daily clinical practice—Real-world evidence from the inflammatory bowel diseases-podcast study
The high percentage of suboptimal disease control (SDC)  in this global, real-world cohort suggests a large disease burden and high unmet medical need in IBD patients. Future analysis should focus on monitoring and responding to SDC in this cohort and on patients' QoL. United European gastroenterology journal 11 May 2024

Physical activity in the prevention and management of inflammatory bowel disease: a systematic review
Physical activity (PA)  seems to be effective in preventing or treating IBDs and their complications. Owing to the low quality of the majority of the studies and their heterogeneity, further research is needed to better understand which type and level of PA may be useful in the prevention and treatment of these diseases. Journal of public health 11 May 2024

Is the European Crohn’s and Colitis organisation (ECCO) e-guide an acceptable and feasible tool for increasing gastroenterologists’ guideline adherence? A mixed methods evaluation
The European Crohn’s and Colitis Organisation (ECCO) e-guide is largely acceptable and feasible for gastroenterologists to use. Aspects of the e-guide could be modified to improve user experience. This study highlights the importance of engaging end-users in the development and evaluation of clinician educational tools. BMC medical education 13 May 2024

The epidemiology of Inflammatory Bowel Disease in Oceania: A systematic review and meta-analysis of incidence and prevalence
The incidence and prevalence of IBD in Oceania is high. The studies were heterogeneous and there were several geographic areas with no information, highlighting the need for more epidemiological studies of IBD. Inflammatory bowel diseases 30 December 2023

Adherence to endoscopic surveillance guidelines for patients with inflammatory bowel disease: An Australian cohort study
Adherence to endoscopic surveillance guidelines with regard to timing of procedures and the utilization of chromoendoscopy is poor. Further clinician education, promotion of the surveillance guidelines and incorporation of chromoendoscopy training as part of the national colonoscopy training program may improve adherence to guidelines. Journal of gastroenterology and hepatology 8 December 2023

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Treatment

Update for surgeons on novel induction treatments for acute severe inflammatory bowel disease associated colitis
JAK-inhibitors and IL-23p19 inhibitors were found to be the most effective agents for inducting remission following failure of standard of care treatment. A significant proportion of patients did not respond, highlighting the inherent challenge in optimizing treatment for moderate to severe IBD-associated colitis. More robust study designs and comparator trials are required. ANZ journal of surgery 7 March 2024

Trends in targeted therapy usage in Inflammatory Bowel Disease: TRENDY study of ENEIDA
Markers that allow for the selection of tailored treatments for individual patients with inflammatory bowel diseases (IBD) are yet to be identified. The author’s aim was to describe trends in real-life treatment usage.  Pharmaceutics 8 May 2024

The effect of probiotics on inflammatory bowel disease: Remission and relapse rate: A systematic review and meta-analysis
Probiotics can significantly ameliorate the remission rate and reduce the relapse rate in IBD patients. Giving probiotics that contain particular strains can increase the remission rate and reduce the relapse rate in IBD.  Udayana journal of internal medicine 5 May 2024

Therapeutic sequencing in inflammatory bowel disease: Determining the optimal position of vedolizumab for long-term Crohn’s disease control using real-world evidence
This simulation model using real-world evidence indicates that positioning Vedolizumab (VDZ)  or adalimumab (ADA) as the first biologic is likely to lead to improved long-term patient outcomes when compared to administering these treatments later or starting with infliximab (IFX) monotherapy. United European gastroenterology journal 8 May 2024

Difficult-to-treat inflammatory bowel disease: Effectiveness and safety of 4th and 5th lines of treatment
In this first real-world setting, risankizumab could have a longer persistence rate as 4th line treatment for IBD than other agents. Persistence of biological agents was greater in Crohn's disease than in ulcerative colitis. More studies are needed to compare treatment efficacy in patients with difficult-to-treat IBD. United European gastroenterology journal 9 April 2024

People with Inflammatory Bowel Disease prefer Cognitive Behavioral Therapy for fatigue management: A conjoint analysis
This study helps provide therapists and program developers clear direction on patient preferences when it comes to developing new psychological programs that address fatigue in IBD. Digestive diseases and sciences 11 May 2024

Steroid therapy in patients with inflammatory bowel disease complicating diabetes diagnosis
This review aims to present the issue of type 1 diabetes in patients treated with steroid therapy for inflammatory bowel disease, and to summarize the current state of knowledge, so that in the future it will result in an accurate diagnosis and implementation of appropriate treatment. Quality in sport 11 May 2024

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E-books

This is just a sample of the e-books the library subscribes to – you will need your library login

• Gastrointestinal and liver pathology (2024)
• Robotic surgery of colon and rectum (2024)
• Pediatric inflammatory bowel disease (2023)
• Crohn's disease and ulcerative colitis : a complete guide for patients (2023)
• Difficult decisions in colorectal surgery (2023)
• Management of inpatient inflammatory bowel disease : a comprehensive handbook (2022)
• Atlas of inflammatory bowel disease-associated intestinal cancer : examining the macroscopic images of small and large intestine (2022)
• Inflammatory bowel disease : pathogenesis, diagnosis and management (2021)
• Sleisenger and Fordtran's gastrointestinal and liver disease : pathophysiology / diagnosis / management (2021)

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Journals

This is just a sample of the journals the library subscribes to – you will need your library login

• Crohn's & colitis 360
• Inflammatory intestinal diseases

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